[1]李侃,李华钢,谢斐,等.脑深静脉窦血栓形成血管内治疗的安全性和有效性:单中心经验和汇总分析[J].卒中与神经疾病杂志,2024,31(06):577-582.[doi:10.3969/j.issn.1007-0478.2024.06.013]
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脑深静脉窦血栓形成血管内治疗的安全性和有效性:单中心经验和汇总分析()
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《卒中与神经疾病》杂志[ISSN:1007-0478/CN:42-1402/R]

卷:
第31卷
期数:
2024年06期
页码:
577-582
栏目:
论著
出版日期:
2024-12-20

文章信息/Info

文章编号:
1007-0478(2024)06-0577-06
作者:
李侃李华钢谢斐刘煜敏梅斌孙冬
432800 湖北省大悟县人民医院神经内科(李侃); 武汉大学中南医院神经内科[李华钢 谢斐 刘煜敏 梅斌 孙冬(通信作者)]
关键词:
血管内治疗 脑深静脉窦血栓形成 窦内溶栓 机械取栓
分类号:
R743.9
DOI:
10.3969/j.issn.1007-0478.2024.06.013
文献标志码:
A
摘要:
目的 分析药物难治性脑深部静脉窦血栓形成(Deep cerebral venous sinus thrombosis,DCVST)患者接受血管内治疗(Endovascular Treatment,EVT)的安全性和有效性。方法 回顾性分析2018年1月-2022年12月在本院接受溶栓和/或取栓治疗的药物难治性DCVST患者,观察所有患者的临床结局、放射学特征、不良反应和手术过程,同时结合以往发表的DCVST患者EVT的文献数据进行汇总分析,采用二元回归模型分析DCVST患者接受EVT后影响临床转归的因素。结果 共纳入9例接受EVT的DCVST患者,其中3例为单纯静脉窦内溶栓,6例为静脉窦内支架取栓联合接触溶栓; 术后第7 d有4例(44.4%)患者脑深部静脉窦完全再通,5例为部分再通; 术后血肿扩大1例(11.1%); 8例患者(88.9%)获得了临床良好预后(定义为术后第90 d改良Rankin量表评分0~1分)。在汇总分析中共纳入46例接受EVT的DCVST患者,其中60.9%获得临床良好预后,80.4%获得完全或部分再通; 3例(8.8%)术后出现血肿扩大。二元回归分析显示,完全或部分再通(β=3.214,P=0.004)和术前较高的GCS评分(β=-0.379,P=0.013)与临床良好预后显著相关。结论 EVT可能是药物难治性DCVST的一种安全有效的治疗方法。

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更新日期/Last Update: 2024-12-20