参考文献/References:
[1] Almendros I, Wang Y, Gozal D. The polymorphic and contradictory aspects of intermittent hypoxia[J]. Am J Physiol Lung Cell Mol Physiol, 2014, 307(2): L129-L140.
[2] Parrino L, Ferri R, Zucconi M, et al. Commentary from the Italian Association of Sleep Medicine on the AASM manual for the scoring of sleep and associated events: for debate and discussion[J]. Sleep Med, 2009, 10(7): 799-808.
[3] Benjafield AV, Ayas NT, Eastwood PR, et al. Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis[J]. Lancet Respir Med, 2019, 7(8): 687-698.
[4] Culebras A. Sleep, stroke and poststroke[J]. Neurol Clin, 2012, 30(4): 1275-1284.
[5] Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges[J]. Lancet Neurol, 2010, 9(7): 689-701.
[6] Wardlaw JM, Smith C, Dichgans M. Small vessel disease: mechanisms and clinical implications[J]. Lancet Neurol, 2019, 18(7): 684-696.
[7] Bokura H, Kobayashi S, Yamaguchi S, et al. Silent brain infarction and subcortical white matter lesions increase the risk of stroke and mortality: a prospective cohort study[J]. J Stroke Cerebrovasc Dis, 2006, 15(2): 57-63.
[8] Iliff JJ, Goldman SA, Nedergaard M. Implications of the discovery of brain lymphatic pathways[J]. Lancet Neurol, 2015, 14(10): 977-979.
[9] K?ari E, Herrmann FR, Gold G, et al. Association of cortical microinfarcts and cerebral small vessel pathology in the ageing brain[J]. Neuropathol Appl Neurobiol, 2017, 43(6): 505-513.
[10] Charidimou A, Linn J, Vernooij MW, et al. Cortical superficial siderosis: detection and clinical significance in cerebral amyloid angiopathy and related conditions[J]. Brain, 2015, 138(8): 2126-2139.
[11] Charidimou A, Boulouis G, Roongpiboonsopit D, et al. Cortical superficial siderosis multifocality in cerebral amyloid angiopathy: A prospective study[J]. Neurology, 2017, 89(21): 2128-2135.
[12] Shiel KP, Patrick JH, Smith EE, et al. Nocturnal hypoxemia is associated with white matter hyperintensities in patients with a minor stroke or transient ischemic attack[J]. Journal of Clinical Sleep Medicine, 2015, 11(12): 1417-1424.
[13] Del Brutto Oscar H,Mera Robertino M,Zambrano Mauricio et al. Relationship between obstructive sleep apnea and neuroimaging signatures of cerebral small vessel disease in community-dwelling older adults. The Atahualpa Project[J].Sleep Med, 2017, 37(undefined): 10-12.
[14] Ho BL, Tseng PT, Lai CL, et al. Obstructive sleep apnea and cerebral white matter change: a systematic review and meta-analysis[J]. J Neurol, 2018, 265(7): 1643-1653.
[15] Huang Y, Yang C, Yuan RZ, et al. Association of obstructive sleep apnea and cerebral small vessel disease: a systematic review and meta-analysis[J]. Sleep, 2020, 43(4): zsz264.
[16] Alvarez-Sabín J, Romero O, Delgado P, et al. Obstructive sleep apnea and silent cerebral infarction in hypertensive individuals[J]. J Sleep Res, 2018, 27(2): 232-239.
[17] Song TJ, Park JH, Choi KH, et al. Moderate-to-severe obstructive sleep apnea is associated with cerebral small vessel disease[J]. Sleep Med, 2017, 30(undefined): 36-42.
[18] Chokesuwattanaskul A, Lertjitbanjong P, Thongprayoon C, et al. Impact of obstructive sleep apnea on silent cerebral small vessel disease: a systematic review and meta-analysis[J]. Sleep Med, 2020, 68(undefined): 80-88.
[19] Huang S, Wang D, Zhou HQ, et al. Neuroimaging Consequences of cerebral small vessel disease in patients with obstructive sleep apnea-hypopnea syndrome[J]. Brain Behav, 2019, 9(8): e01364.
[20] Blackwell T, Yaffe K, Laffan A, et al. Associations between sleep-disordered breathing, nocturnal hypoxemia, and subsequent cognitive decline in older community-dwelling men: the Osteoporotic Fractures in Men Sleep Study[J]. J Am Geriatr Soc, 2015, 63(3): 453-461.
[21] Kanbay A, Demir NC, Tutar N, et al. The effect of CPAP therapy on insulin-like growth factor and cognitive functions in obstructive sleep apnea patients[J]. Clin Respir J, 2017, 11(4): 506-513.
[22] Vanek J, Prasko J, Genzor S, et al. Obstructive sleep apnea, depression and cognitive impairment[J]. Sleep Med, 2020, 72((undefined): 50-58.
[23] Latreille V, Willment KC, Sarkis RA, et al. Neuropsychological correlates of obstructive sleep apnea severity in patients with epilepsy[J]. Epileptic Disord, 2019, 21(1): 78-86.
[24] Gaeta AM, Benítez ID, Jorge C, et al. Prevalence of obstructive sleep apnea in Alzheimer’s disease patients[J]. J Neurol, 2020, 267(4): 1012-1022.
[25] Chen XQ, Mobley WC. Alzheimer disease pathogenesis: insights from molecular and cellular biology studies of oligomeric Aβ and Tau species[J]. Front Neurosci, 2019, 13(undefined): 659.
[26] Yun CH, Lee HY, Lee SK, et al. Amyloid burden in obstructive sleep apnea[J]. J Alzheimers Dis, 2017, 59(1): 21-29.
[27] Kong Weili,Zheng Yun,Xu Wei et al. Biomarkers of Alzheimer’s disease in severe obstructive sleep apnea-hypopnea syndrome in the Chinese population.[J].Eur Arch Otorhinolaryngol, 2020, undefined(undefined): undefined.
[28] Liguori Claudio,Mercuri Nicola Biagio,Izzi Francesca et al. Obstructive Sleep Apnea is Associated With Early but Possibly Modifiable Alzheimer’s Disease Biomarkers Changes.[J].Sleep, 2017, 40(5): undefined.
[29] Dostálová V, Kole(ˇoverc)kárová S, Kuka M, et al. Effects of continuous positive airway pressure on neurocognitive and neuropsychiatric function in obstructive sleep apnea[J]. J Sleep Res, 2019, 28(5): e12761.
[30] Ng SS, Chan TO, To KW, et al. Prevalence of obstructive sleep apnea syndrome and CPAP adherence in the elderly Chinese population[J]. PLoS One, 2015, 10(3): e0119829.
[31] Wu Shu Qing,Liao Qing Chi,Xu Xing Xiang et al. Effect of CPAP therapy on C-reactive protein and cognitive impairment in patients with obstructive sleep apnea hypopnea syndrome.[J].Sleep Breath, 2016, 20(4): 1185-1192.
[32] Troussière AC, Charley CM, Salleron J, et al. Treatment of sleep apnoea syndrome decreases cognitive decline in patients with Alzheimer’s disease[J]. J Neurol Neurosurg Psychiatry, 2014, 85(12): 1405-1408.
[33] Edwards BA, Bristow C, O’driscoll DM, et al. Assessing the impact of diet, exercise and the combination of the two as a treatment for OSA: A systematic review and meta-analysis[J]. Respirology, 2019, 24(8): 740-751.
[34] Wang ML, Wang C, Tuo M, et al. Cognitive effects of treating obstructive sleep apnea: a Meta-Analysis of randomized controlled trials[J]. J Alzheimers Dis, 2020, 75(3): 705-715.