[1]顾玉玲,盛卫东,俞冲,等.脑卒中后抑郁对患者免疫功能的影响[J].卒中与神经疾病杂志,2016,23(06):420-423.[doi:10.3969/j.issn.1007-0478.2016.06.009]
　Gu Yuling,Sheng Weidong,Yu Chong,et al.Immune function in patients with post stroke depression[J].Stroke and Nervous Diseases,2016,23(06):420-423.[doi:10.3969/j.issn.1007-0478.2016.06.009]
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脑卒中后抑郁对患者免疫功能的影响()
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《卒中与神经疾病》杂志[ISSN:1007-0478/CN:42-1402/R]

卷:
第23卷
期数:
2016年06期
页码:
420-423
栏目:
论 著
出版日期:
2016-12-30

文章信息/Info

Title:
Immune function in patients with post stroke depression
文章编号:
1007-0478(2016)06-0420-04
作者:
顾玉玲; 盛卫东; 俞冲; 王海
226006 江苏省南通大学附属南通第三医院康复科[顾玉玲 盛卫东 俞冲(通信作者)王海]
Author(s):
Gu Yuling; Sheng Weidong; Yu Chong; et al.
Department of Neurological Rehabilitation,Nantong Third People's Hospital of Nantong University,Nantong 226006
关键词:
脑卒中 抑郁症 T细胞亚群 免疫球蛋白
Keywords:
Stroke Depression T lymphocyte subsets Immunoglobulin
分类号:
R749.1
DOI:
10.3969/j.issn.1007-0478.2016.06.009
文献标志码:
A
摘要:
顾玉玲 盛卫东 俞冲 王海
Abstract:
ObjectiveTo investigate the immune function of post stroke depression(PSD)patients.Methods 90 stroke patients(half of which with depression)admitted in third people's Hospital from October 2012 to October 2015 were collected and analyzed. At the meantime, 30 depression patients and 30 healthy people were collected as control groups.Then analyzed expression of T lymphocyte subsets, immunoglobulin and complement in peripheral blood of all the people.Results The T lymphocyte subsets in both PSD group and depression group were significantly lower than those in healthy group(P<0.05)and had statistical significance.Obviously, the PSD group was more lower. Compared to healthy group, IgG,IgA and IgM in the PSD group and depression group were lower.PSD group was even lower than the depression group(P<0.05).IgG,IgA and IgM levels in stroke group and healthy group were in the normal range, but the stroke group was lower compared to the healthy group(P<0.05). Complement C3 level in both PSD group and depression group increased,while PSD group was higher(P<0.05).However,the levels of four groups were in normal range,and there was nostatistical significance among the four groups(P>0.05).Conclusion Patients with PSD have immune function impaired to some extent,and may become worser with the disease progress. We need to strengthen the dynamic monitoring of related immune indexes,and do something for PSD patients with lower immunity to interpose early and prevent the progression of the disease.

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更新日期/Last Update: 2016-12-20