[1]程越朋,孙书军,杨光,等.影响急性脑梗死患者二级预防用药依从性的调查研究[J].卒中与神经疾病杂志,2017,24(01):30-33.[doi:10.3969/j.issn.1007-0478.2017.01.008]
　Cheng Yuepeng,Sun Shujun,Yang Guang,et al.Investigation of influencing patients' compliance of the secondary prevention of cerebral infarction[J].Stroke and Nervous Diseases,2017,24(01):30-33.[doi:10.3969/j.issn.1007-0478.2017.01.008]
点击复制

影响急性脑梗死患者二级预防用药依从性的调查研究()
分享到：

《卒中与神经疾病》杂志[ISSN:1007-0478/CN:42-1402/R]

卷:
第24卷
期数:
2017年01期
页码:
30-33
栏目:
论 著
出版日期:
2017-02-26

文章信息/Info

Title:
Investigation of influencing patients' compliance of the secondary prevention of cerebral infarction
文章编号:
1007-0478(2017)01-0030-04
作者:
程越朋; 孙书军; 杨光; 史益男; 李龙; 刘芳; 王爽; 孙鑫; 祁梅; 高政
116021 大连市第五人民医院神经内科(程越朋 孙书军 杨光 史益男 李龙 刘芳 王爽 孙鑫 祁梅); 大连医科大学附属三院[高政(通信作者)]
Author(s):
Cheng Yuepeng; Sun Shujun; Yang Guang; et al.
Department of Neurology,the Fifth People' Hospital,Dalian 116021
关键词:
脑梗死 依从性 二级预防 抗血小板聚集 他汀
Keywords:
Cerebral infarction Compliance Secondary prevention Antiplatelet Statin
分类号:
R743
DOI:
10.3969/j.issn.1007-0478.2017.01.008
摘要:
目的 了解大连西部地区急性脑梗死患者住院期间及出院180 d后二级预防药物和行为修正的依从性现状及依从性下降原因。方法 调查2014年4月1日～2015年1月31日符合入组标准的急性脑梗死患者对于抗血小板药聚集药物、他汀药物、降压药物、降糖药物、抗凝药物治疗的使用率、戒烟行为修正率并随访180 d。结果 入组患者中使用他汀等药物及抗凝药物依从性偏差,分别是50.1%和40.4%; 不同药物二级预防依从性下降的原因不同; 180 d后随访发现急性脑梗死发生率为6.4%。结论 医生应关注患者有明确循证医学依据的二级预防药物及行为修正的依从性,并了解其下降的原因,采取针对措施提高患者药物治疗及行为修正的依从性。
Abstract:
ObjectiveTo investigate the compliance and its decreasing reasons of the secondary preventive drugs' use and the behavior modification in patients with acute infarction in the western area during hospitalization and the follow-up for 180 days after discharge.Methods From April 1,2014 to November 30,2014,the use frequency of the secondary preventive drugs(including antiplatelet drug,statin,antihypertensive drug,hypoglycemic agent and anticoagulant drug)and the behavior modification rate of quitting smoking in all patients complied with the inclusion criteria of acute cerebral infarction were investigated,and the cases were followed up for 180 days.Results The compliances of statins and anticoagulant drugs were poor(50.1% and 40.4%,respectively).The decreasing reasons of compliance for the different secondary preventive drugs were different.After the follow-up for 180 days,the incidence of cerebral infarction was found to be 6.4%.Conclusion Doctors should pay close attention to patients' compliance of the secondary preventive drugs and behavior modifications according to the evidence-based medicine,and the decreasing reasons to improve patients' compliance.

参考文献/References:

[1] Meissner I,Whisnant JP,Wm G.Hypertension management and stroke recurrence in a community(Rochester,Minnesota,1950-79)[J].Stroke,1988,19(4):459-463.
[2] Geust M,Blakely JA,Hachinski V,et al.A secondary prevention,rando-mized trial of suloctidil in patients with a recent history of throm-Boembolic stroke[J].Stroke,1985,16(6):416-424.
[3] 赵连成,武阳丰,周北凡,等.体质指数与冠心病、脑卒中发病的前瞻性研究[J].中华心血管病杂志,2002,30(7):430-433.
[4] Hardie K,Gj H,Jamrozik K,et al.Ten-year risk of firstrecurrent stroke and disability after first-ever stroke in the PerthCommunity Stroke Study[J].Stroke,2004,35(3):731-735.
[5] Hamann GF,Weimar C,Glahn J,et al.Adherence to secondary stroke prevention strategies - Results from the German stroke data bank[J].Cerebrovascular Diseases,2003,15(4):282-288.
[6] 马锐华,王拥军,王春雪,等.脑梗死/短暂性脑缺血发作住院患者二级预防依从性研究及90天随访[J].中华医学杂志,2008,88(37):2618-2622.
[7] 赵红梅,刘文华,王筱萌,等.复发性脑梗死的危险因素及病因分析[J].中华老年心血管病杂志,2013,15(1):42-45.
[8] 中华医学会神经病学分会中华医学会神经病学分会脑血管病学组.中国缺血性脑卒中和短暂性脑缺血发作二级预防指南2014[J].中华神经科杂志,20l5,48(4):258-273.
[9] 吴敌,马锐华,王伊龙,等.缺血性卒中二级预防的药物依从性调查[J].中华内科杂志,2005,44(7):506-508.
[10] Glader EL,Sjölander M,Eriksson M,et al.Persistent use of secondary preventive drugs declines rapidly during the first 2 years after stroke[J].Stroke,2010,41(2):397-401.
[11] 万志荣,何向楠,李继来,等.缺血性脑卒中患者二级预防用药依从性的现状研究[J].中国医药指南,2014,12(4):1-3.
[12] 宋波,杨光,高远,等.他汀类药物在缺血性卒中和短暂性脑缺血发作二级预防中的应用现状及其依从性[J].中华神经科杂志,2012,45(2):107-111.
[13] 蒋立新,李希,李静,等.中国动脉粥样硬化性缺血性脑卒中患者他汀类药物应用现况调查[J].中华流行病学杂志,2010,31(8):925-928.
[14] Wang CJ,Yang ZH,Wang CX,et al.Significant underuse of warfarin in patients with nonvalvular atrial fibrillation:results from the China National stroke registry[J].Journal of Stroke & Cerebrovascular Diseases,2014,23(5):1157-1163.
[15] 于天霞,马丽丽,杜文贞.华法林与阿司匹林对脑梗死伴心房颤动患者二级预防的对比研究[J].中华老年医学杂志,2014,33(5):532-533.

更新日期/Last Update: 2017-02-20