[1]于芳苹 张瑜 赵迎春 杨永益 吴英.FVEP无创颅内压监测在高血压性脑出血并颅内压增高患者中的临床应用[J].卒中与神经疾病杂志,2019,26(01):64-67,72.[doi:10.3969/j.issn.1007-0478.2019.01.015]
　Yu Fangping*,Zhang Yu,Zhao Yingchun,et al.Clinical application of noninvasive intracranial pressure monitoring based on flash visual evoked potentials in treatment of patients with hypertensive intracerebral hemorrhage[J].Stroke and Nervous Diseases,2019,26(01):64-67,72.[doi:10.3969/j.issn.1007-0478.2019.01.015]
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FVEP无创颅内压监测在高血压性脑出血并颅内压增高患者中的临床应用()
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《卒中与神经疾病》杂志[ISSN:1007-0478/CN:42-1402/R]

卷:
第26卷
期数:
2019年01期
页码:
64-67,72
栏目:
论 著
出版日期:
2019-02-26

文章信息/Info

Title:
Clinical application of noninvasive intracranial pressure monitoring based on flash visual evoked potentials in treatment of patients with hypertensive intracerebral hemorrhage
文章编号:
1007-0478(2019)01-0064-05
作者:
于芳苹 张瑜 赵迎春 杨永益 吴英
201699 上海交通大学附属第一人民医院松江分院老年干部科(于芳苹 杨永益),神经内科[张瑜 赵迎春(通信作者)吴英]
Author(s):
Yu Fangping*;  Zhang Yu;  Zhao Yingchun;  et al
*Department of Elderly Cadre Ward, Songjiang Hospital Affiliated to First People's Hospital, Shanghai Jiaotong University, Shanghai 201699
关键词:
高血压性脑出血 无创颅内压监测 甘露醇 颅内压增高
Keywords:
Hypertensive intracerebral hemorrhage Noninvasive intracranial pressure monitoring Mannitol Intracraninal hypertension
分类号:
R743.34
DOI:
10.3969/j.issn.1007-0478.2019.01.015
文献标志码:
A
摘要:
目的 探讨闪光视觉诱发电位(FVEP)无创颅内压监测技术在高血压性脑出血(HICH)并颅内压增高患者中的临床应用。方法 选取本院神经内科和老年科住院的高血压性脑出血(HICH)并颅内压(ICP)增高患者102例,随机分为FVEP无创颅内压监测组(实验组)和非监测组(对照组); 所有实验组病例经FVEP监测ICP和立即行腰穿检查测ICP,治疗上给予甘露醇脱水降颅内压; 记录2组患者甘露醇使用量以及肾功能情况,评估FVEP无创颅内压监测技术指导临床调整脱水剂的应用效果; 记录2组患者GOS评分,评价FVEP无创颅内压监测技术在HICH并颅内压增高患者临床治疗中的参考价值。结果 实验组患者入院时FVEP无创颅内压测得值与腰椎穿刺颅内压测量值比较无明显差异[(195.76±13.24)mmH2O vs(197.04±11.98)mmH2O, P>0.05]; 实验组甘露醇使用量较对照组明显减少(P<0.05); 2组血肌酐、尿素氮水平比较无明显差异(P>0.05); 实验组治愈率高于对照组(χ2=3.889, P=0.048)。结论 FVEP无创颅内压监测技术可以替代有创颅内压监测技术,应用FVEP无创颅内压监测技术可以及时调整并减少HICH并颅内压增高患者脱水剂甘露醇的用量,改善HICH并颅内压增高患者的病情和预后。
Abstract:
ObjectiveTo investigate the application value of the noninvasive intracranial pressure monitoring based on flash visual evoked potentials in patients with hypertensive intracerebral hemorrhage(HICH).Methods A case-control association study containning 102 patients with hypertensive intracerebral hemorrhage who had sought medical treatment in our neurology and cardre's departments was carried out in Songjiang district, Shanghai. 102 cases were randomly divided into FVEP noninvasive intracranial pressure monitoring group(experimental group)and the non-monitoring group(control group). The experimental group were examined lumbar puncture immediately after intracranial pressure was monitored by FVEP. Mannitol was used to dehydration treatment of intracraninal hypertension patients. The serum concentrations of creatinine and urea nitrogen were recorded to assess the renal function. The mannitol usage was used to evaluate the value of FVEP noninvasive intracranial pressure monitoring techniques in guiding the adjustment of dehydrating agent. The Glasgow prognosis scores(GOS)were evaluated for patients' prognosis between two groups.Results There was no statistical significance between FVEP noninvasive intracranial pressure measurement and lumbar puncture intracranial pressure measurement [(195.76±13.24)mmH2O vs(197.04±11.98)mmH2O, P>0.05]. The dosage of mannitol in the experimental group was significantly lower than that in the control group(P<0.05), and the serum creatinine and urea nitrogen concentrations between two groups were not statistically significant(P>0.05).The cure rate of the experimental group is higher than that of the control group(χ2=3.889, P=0.048).Conclusion FVEP noninvasive intracranial pressure monitoring technology could replace invasive intracranial pressure monitoring technology in monitoring intracranial pressure for HICH patients. The application of FVEP noninvasive intracranial pressure technique could reduce the dosage of dehydrating mannitol and improve the prognosis of patients with HICH.

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备注/Memo

备注/Memo:
基金项目:上海市科学技术委员会资助项目(16411973000)
作者单位:201699 上海交通大学附属第一人民医院松江分院老年干部科(于芳苹 杨永益),神经内科[张瑜 赵迎春(通信作者)吴英]
更新日期/Last Update: 2019-02-20