[1]张青青 郭孟敏 马文彬 赵斌 李明远 陈芳.外源性神经节苷脂相关性吉兰-巴雷综合征的临床特征及肌电图表现(附3例报道)[J].卒中与神经疾病杂志,2019,26(03):337-341345.[doi:10.3969/j.issn.1007-0478.2019.03.020]
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外源性神经节苷脂相关性吉兰-巴雷综合征的临床特征及肌电图表现(附3例报道)()
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《卒中与神经疾病》杂志[ISSN:1007-0478/CN:42-1402/R]

卷:
第26卷
期数:
2019年03期
页码:
337-341345
栏目:
论 著
出版日期:
2019-06-25

文章信息/Info

文章编号:
1007-0478(2019)03-0337-06
作者:
张青青 郭孟敏 马文彬 赵斌 李明远 陈芳
256603 山东省滨州医学院附属医院神经内科[张青青 郭孟敏 马文彬 赵斌 李明远 陈芳(通信作者)]
关键词:
外源性神经节苷脂 吉兰-巴雷综合征 不良反应 临床特点 治疗
分类号:
R745.4+3
DOI:
10.3969/j.issn.1007-0478.2019.03.020
文献标志码:
A
摘要:
目的 探讨外源性神经节苷脂相关性吉兰-巴雷综合征(GBS)的临床特点、发病机制及治疗措施。方法 回顾性分析3例外源性神经节苷脂相关性GBS患者临床资料。结果 3例男性老年患者自开始用药后7~14 d起病,临床表现以进行性加重的四肢无力为主要表现,四肢软瘫,腱反射消失,无感觉障碍,肌电图(EMG)检查提示轴索损害为主,符合外源性神经节苷脂相关性GBS诊断; 治疗上以尽早停用外源性神经节苷脂并以迅速经静脉注射人血免疫球蛋白或行血浆置换治疗为主。结论 外源性神经节苷脂可能与GBS的发生与进展有关,通常患者预后不良。

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更新日期/Last Update: 2019-06-25