[1]李晓鹏 李彩杰 姜方超 马静 李丹 张彩霞 赵鹏.误诊为病毒性脑炎的富亮氨酸胶质瘤失活1蛋白抗体脑炎1例报道并文献复习[J].卒中与神经疾病杂志,2020,27(03):368-370.[doi:10.3969/j.issn.1007-0478.2020.03.020]
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误诊为病毒性脑炎的富亮氨酸胶质瘤失活1蛋白抗体脑炎1例报道并文献复习()
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《卒中与神经疾病》杂志[ISSN:1007-0478/CN:42-1402/R]

卷:
第27卷
期数:
2020年03期
页码:
368-370
栏目:
论 著
出版日期:
2020-07-20

文章信息/Info

文章编号:
1007-0478(2020)03-0368-04
作者:
李晓鹏 李彩杰 姜方超 马静 李丹 张彩霞 赵鹏
475000 河南省开封市河南大学第一附属医院神经内科(李晓鹏 姜方超 马静 李丹),中医科(李彩杰),预防保健科(张彩霞); 日本北海道大学[赵鹏(通信作者)]
关键词:
LGI1抗体脑炎 自身免疫性脑炎 病毒性脑炎
分类号:
R512.3
DOI:
10.3969/j.issn.1007-0478.2020.03.020
文献标志码:
A
摘要:
目的 总结1例富亮氨酸胶质瘤失活1蛋白(LGI1)抗体脑炎患者的临床表现和辅助检查特点,以提高临床医师对该病的认识。方法 回顾性分析1例富亮氨酸胶质瘤失活1蛋白(LGI1)抗体脑炎患者的临床资料,并结合文献进行分析。结果 患者,男,67岁,以认知功能障碍、癫痫发作、精神行为异常、顽固性低钠血症为主要临床表现,头部磁共振成像(MRI)显示双侧海马异常信号,脑脊液抗体检测发现LGI1抗体阳性,故确诊LGI1抗体脑炎,给予激素治疗后症状明显改善。结论 对于老年期起病,临床表现为认知功能障碍、癫痫发作、精神行为异常、顽固性低钠血症的患者,应高度怀疑LGI1抗体脑炎的可能。

参考文献/References:

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备注/Memo

备注/Memo:
(2019-09-28 收稿)基金项目:河南省卫计委科研项目(201404021)
更新日期/Last Update: 2020-07-20