参考文献/References:
[1] Bonfili L,Cecarini V,Gogoi O,et al.Microbiota modulation as preventative and therapeutic approach in Alzheimer's disease[J].FEBS J,2021,288(9):2836-2855.
[2] Kobayashi Y,Sugahara H,Shimada KSE,et al.Therapeutic potential of bifidobacterium breve strain A1 for preventing cognitive impairment in Alzheimer's disease[J].Sci Rep,2017,7(1):13510.
[3] Kim H,Kim S,Park SJ,et al.Administration of bifidobacterium bifidum BGN4 and bifidobacterium longum BORI improves cognitive and memory function in the mouse model of Alzheimer's disease[J].Front Aging Neurosci,2021,13:709091.
[4] Zhu GS,Zhao JX,Zhang H,et al.Administration of bifidobacterium breve improves the brain function of Aβ1-42-treated mice via the modulation of the gut microbiome[J].Nutrients,2021,13(5):1602.
[5] Wang XY,Sun GA,Feng T,et al.Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression[J].Cell Res,2019,29(10):787-803.
[6] CAO J,AMAKYE WK,QI C,et al.Bifidobacterium lactis Probio-M8 regulates gut microbiota to alleviate alzheimer's disease in the APP/PS1 mouse model[J].Eur J Nutr,2021,60(7):3757-3769.
[7] Lee HJ,Lee KE,Kim JK,et al.Suppression of gut dysbiosis by bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice[J].Sci Rep,2019,9(1):11814.
[8] Zhu GS,Guo M,Zhao JX,et al.Integrative metabolomic characterization reveals the mediating effect of bifidobacterium breve on amino acid metabolism in a mouse model of Alzheimer's disease[J].Nutrients,2022,14(4):735.
[9] Abdelhamid M,Zhou CY,Ohno K,et al.Probiotic bifidobacterium breve prevents memory impairment through the reduction of both amyloid-β production and microglia activation in APP knock-in mouse[J].J Alzheimers Dis,2022,85(4):1555-1571.
[10] Xiao JZ,Katsumata N,Bernier F,et al.Probiotic bifidobacterium breve in improving cognitive functions of older adults with suspected mild cognitive impairment: a randomized, double-blind, placebo-controlled trial[J].J Alzheimers Dis,2020,77(1):139-147.
[11] Kobayashi Y,Kuhara T,Oki M,et al.Effects of bifidobacterium breve a1 on the cognitive function of older adults with memory complaints: a randomised, double-blind, placebo-controlled trial[J].Benef Microbes,2019,10(5):511-520.
[12] Nimgampalle M,Kuna Y.Anti-Alzheimer properties of probiotic, lactobacillus plantarum MTCC 1325 in Alzheimer's disease induced albino rats[J].J Clin Diagn Res,2017,11(8):KC01-KC05.
[13] Wang QJ,Shen YE,Wang X,et al.Concomitant memantine and lactobacillus plantarum treatment attenuates cognitive impairments in APP/PS1 mice[J].Aging,2020,12(1):628-649.
[14] Song XP,Zhao ZJ,Zhao YJ,et al.Lactobacillus plantarum DP189 prevents cognitive dysfunction in D-galactose/AlCl3 induced mouse model of Alzheimer's disease via modulating gut microbiota and PI3K/Akt/GSK-3β signaling pathway[J].Nutr Neurosci,2022,25(12):2588-2600.
[15] Musa NH,Mani V,Lim SM,et al.Lactobacilli-fermented cow's milk attenuated lipopolysaccharide-induced neuroinflammation and memory impairment in vitro and in vivo[J].J Dairy Res,2017,84(4):488-495.
[16] El Sayed NS,Kandil EA,Ghoneum MH.Probiotics fermentation technology, a novel kefir product, ameliorates cognitive impairment in Streptozotocin-Induced sporadic Alzheimer's disease in mice[J].Oxid Med Cell Longev,2021,2021:5525306.
[17] Patel C,Pande S,Acharya S.Potentiation of anti-Alzheimer activity of curcumin by probiotic lactobacillus rhamnosus UBLR-58 against scopolamine-induced memory impairment in mice[J].Naunyn Schmiedebergs Arch Pharmacol,2020,393(10):1955-1962.
[18] Hwang YH,Park S,Paik JW,et al.Efficacy and safety of lactobacillus plantarum C29-fermented soybean(DW2009)in individuals with mild cognitive impairment: a 12-week, multi-center, randomized, double-blind, placebo-controlled clinical trial[J].Nutrients,2019,11(2):305.
[19] Bonfili L,Cecarini V,Berardi S,et al.Microbiota modulation counteracts Alzheimer's disease progression influencing neuronal proteolysis and gut hormones plasma levels[J].Sci Rep,2017,7(1):2426.
[20] Bonfili L,Cecarini V,Gogoi O,et al.Gut microbiota manipulation through probiotics oral administration restores glucose homeostasis in a mouse model of Alzheimer's disease[J].Neurobiol Aging,2020,87:35-43.
[21] Bonfili L,Gong CM,Lombardi F,et al.Strategic modification of gut microbiota through oral bacteriotherapy influences hypoxia inducible factor-1α: therapeutic implication in Alzheimer's disease[J].Int J Mol Sci,2021,23(1):357.
[22] Abraham D,Feher J,Scuderi GL,et al.Exercise and probiotics attenuate the development of Alzheimer's disease in transgenic mice: role of microbiome[J].Exp Gerontol,2019,115:122-131.
[23] Shamsipour S,Sharifi G,Taghian F.Impact of interval training with probiotic(L. plantarum / bifidobacterium bifidum)on passive avoidance test, ChAT and BDNF in the hippocampus of rats with Alzheimer's disease[J].Neurosci Lett,2021,756:135949.
[24] Lee DY,Shin YJ,Kim JK,et al.Alleviation of cognitive impairment by gut microbiota lipopolysaccharide production-suppressing Lactobacillus plantarum and bifidobacterium longum in mice[J].Food Funct,2021,12(21):10750-10763.
[25] Mohammadi G,Dargahi L,Peymani A,et al.The effects of probiotic formulation pretreatment(lactobacillus helveticus R0052 and bifidobacterium longum R0175)on a lipopolysaccharide rat model[J].J Am Coll Nutr,2019,38(3):209-217.
[26] Mehrabadi S,Sadr SS.Assessment of probiotics mixture on memory function, inflammation markers, and oxidative stress in an alzheimer's disease model of rats[J].Iran Biomed J,2020,24(4):220-228.
[27] Westfall S,Lomis N,Prakash S.A novel synbiotic delays Alzheimer's disease onset via combinatorial gut-brain-axis signaling in Drosophila melanogaster[J].PLoS One,2019,14(4):e0214985.
[28] Rezaei Asl Z,Sepehri G,Salami M.Probiotic treatment improves the impaired spatial cognitive performance and restores synaptic plasticity in an animal model of Alzheimer's disease[J].Behav Brain Res,2019,376:112183.
[29] Rezaeiasl Z,Salami M,Sepehri G.The effects of probiotic lactobacillus and bifidobacterium strains on memory and learning behavior, long-term potentiation(LTP), and some biochemical parameters in β-amyloid-induced rat's model of Alzheimer's disease[J].Prev Nutr Food Sci,2019,24(3):265-273.
[30] Wang F,Xu T,Zhang YJ,et al.Long-term combined administration of bifidobacterium bifidum TMC3115 and lactobacillus plantarum 45 alleviates spatial memory impairment and gut dysbiosis in APP/PS1 mice[J].FEMS Microbiol Lett,2020,367(7):fnaa048.
[31] Tan CX,Liu Y,Zhang HY,et al.Neuroprotective effects of probiotic-supplemented diet on cognitive behavior of 3xTg-AD mice[J].J Healthc Eng,2022,2022:4602428.
[32] Kaur H,Nagamoto CK,Golovko S,et al.Probiotics ameliorate intestinal pathophysiology in a mouse model of Alzheimer's disease[J].Neurobiol Aging,2020,92:114-134.
[33] Kaur H,Golovko S,Golovko MY,et al.Effects of probiotic supplementation on short chain fatty acids in the AppNL-G-F mouse model of Alzheimer's disease[J].J Alzheimers Dis,2020,76(3):1083-1102.
[34] Kaur H,Nookal S,Singh S,et al.Sex-dependent effects of intestinal microbiome manipulation in a mouse model of Alzheimer's disease [J].Cells,2021,10(9):2370.
[35] Tamtaji OR,Heidari-Soureshjani R,Mirhosseini N,et al.Probiotic and selenium co-supplementation, and the effects on clinical, metabolic and genetic status in Alzheimer's disease: a randomized, double-blind, controlled trial[J].Clin Nutr,2019,38(6):2569-2575.
[36] Xiang S,Ji JL,Li S,et al.Efficacy and safety of probiotics for the treatment of Alzheimer's disease, mild cognitive impairment, and parkinson's disease: a systematic review and meta-analysis[J].Front Aging Neurosci,2022,14:730036.
[37] Zhu GS,Zhao JX,Zhang H,et al.Probiotics for mild cognitive impairment and Alzheimer's disease: a systematic review and meta-analysis[J].FOODS,2021,10(7):1672.
[38] Leblhuber F,Steiner K,Schuetz B,et al.Probiotic supplementation in patients with Alzheimer's dementia-an explorative intervention study[J].Curr Alzheimer Res,2018,15(12):1106-1113.
[39] Agahi A,Hamidi GA,Daneshvar R,et al.Does severity of alzheimer's disease contribute to its responsiveness to modifying gut microbiota? a double blind clinical trial[J].Front Neurol,2018,9:662.
[40] Li XR,Lv C,Song JX,et al.Effect of probiotic supplementation on cognitive function and metabolic status in mild cognitive impairment and Alzheimer's disease: a meta-analysis[J].Front Nutr,2021,8:757673.
[41] Krüger JF,Hillesheim E,Pereira ACSN,et al.Probiotics for dementia: a systematic review and meta-analysis of randomized controlled trials[J].Nutr Rev,2021,79(2):160-170.
[42] Sun J,Xu JX,Yang B,et al.Effect of clostridium butyricum against microglia-mediated neuroinflammation in Alzheimer's disease via regulating gut microbiota and metabolites butyrate[J].Mol Nutr Food Res,2020,64(2):e1900636.
[43] Cogliati S,Clementi V,Francisco M,et al.Bacillus subtilis delays neurodegeneration and behavioral impairment in the Alzheimer's disease model caenorhabditis elegans[J].J Alzheimers Dis,2020,73(3):1035-1052.
[44] Ou ZH,Deng LL,Lu Z,et al.Protective effects of akkermansia muciniphila on cognitive deficits and amyloid pathology in a mouse model of Alzheimer's disease[J].Nutr Diabetes,2020,10(1):12.