[1]吕敏 吕琳 温慧军等. ABCD2评分预测头昏患者发生缺血性脑血管事件风险的研究[J].卒中与神经疾病杂志,2016,23(03):164-166.[doi:10.3969/j.issn.1007-0478.2016.03.005]
　Lv Min,Lv Lin,Wen Huijun,et al. Application of the ABCD2 score to identify ischemic cerebrovascular events of patients with dizziness[J].Stroke and Nervous Diseases,2016,23(03):164-166.[doi:10.3969/j.issn.1007-0478.2016.03.005]
点击复制

 ABCD2评分预测头昏患者发生缺血性脑血管事件风险的研究(/HTML)
分享到：

《卒中与神经疾病》杂志[ISSN:1007-0478/CN:42-1402/R]

卷:
第23卷
期数:
2016年03期
页码:
164-166
栏目:
论 著
出版日期:
2016-06-24

文章信息/Info

Title:
 Application of the ABCD2 score to identify ischemic cerebrovascular events of patients with dizziness
作者:
 吕敏 吕琳 温慧军等
 721008 陕西省宝鸡市中心医院神经内二科[吕敏 温慧军 李永强 潘艳艳(通信作者)],陕西省宝鸡市中医医院脑病科(吕琳)
Author(s):
 Lv Min;  Lv Lin;  Wen Huijun; et al.
 The Second Department of Neurology,Baoji Central Hospital, Baoji 721001
关键词:
 ; 头昏 脑梗死 预测 ABCD2评分
Keywords:
 ;  Dizziness Cerebral infarction Predication ABCD2 Score
分类号:
R743
DOI:
10.3969/j.issn.1007-0478.2016.03.005
文献标志码:
A
摘要:
 目的 探讨ABCD2评分预测短暂性脑缺血发作(TIA)后发生脑梗死的风险。方法 收集118例以头昏为主要症状患者的临床资料。对所有患者在首诊时使用ABCD2评分进行评价,并将入组者分为低危组(1～3分),中危组(4～5分)和高危组(6～7分)。入组患者均在入组后即进行头颅CT检查,在48～72 h内进行核磁共振成像检查,观察弥散加权序列是否出现高信号,以确定是否发生脑血管病事件。出院后对入组者进行长达6个月的随访,观察脑血管事件的发生率。结果 入组118例患者,其中男57例,女61例; 年龄62-77 岁,平均年龄(65.8±11.6)岁。高危组37例,中危组29例,低危组52例。经证实入组患者中15例(12.7%)发生脑血管病事件,经影像学证实均为脑梗死。高危组中11例(29.7%)发生脑梗死,中危组3例(10.3%)发生脑梗死,而低危组患者在随访观察期内仅有1例(1.9%)发生脑梗死,3组间差异具有显著统计学意义(P<0.01)。结论 ABCD2评分系统可有效预测头昏患者发生脑血管病事件的风险。该评分方法的应用对早期干预,预防缺血性脑血管疾病的进展,改善预后有积极意义。
Abstract:
 ObjectiveDizziness may be a premonitory symptom of cerebrovascular events. The ABCD2 score can predicts the risk of stroke after transient ischemic attack(TIA). We evaluated whether this score would also identify cerebrovascular events among patients with dizziness.Methods We collected data of 118 patients whose chief complaint was dizziness. ABCD2 scoring was applied to all the patients at the first visit. Then they were grouped according to the scores as low- risk group(1-3), mid-risk group(4-5)and high-risk group(6-7). CT scan was given after they were enrolled, and MRI was given within 48-72 hours. Ischemic cerebrovascular events were identified by the high signal in diffused weighted image(DWI). Then a follow-up up to 6 months was carried out to observe the probability of cerebrovascular events among the enrolled patients. The data were analyzed, and the differences about the incidence of cerebrovascular disease were compared among the groups.Results Of all the 118 patients, 57 were male and 61were female, the age range was 62-77 years old,average 65.8±11.6 years old. 37 patients were in high-risk group, 29 patients were in mid-risk group and other 52 patients were in low-risk group. 15 cases(12.7%)occurred cerebrovascular event, all of which were ischemic strokes identified by imaging. 11 cases(29.7%)in the high-risk group occurred cerebral infarction which was more than the occurred cases in the mid-risk group(3 cases, 10.3%)and the low-risk group(1 case, 1.9%)(P<0.01).Conclusion The ABCD2 score may provide useful information to predict the risk of cerebrovascular events in patients with dizziness. The application of the ABCD2 scoring may has positive value in early intervention, prevention of disease progress and improving prognosis of ischemic cerebrovascular events.

参考文献/References:

 [1] Newman-Toker D,Hsieh YH,Camargo CA,et al.Spectrum of dizziness visits to US emergency departments:cross-sectional analysis from a nationally representative sample[J].Mayo Clin Proc,2008,83(7):765-775.
[2] Cheung CS,Mak PS,Manley KV,et al.Predictors of important neurological causes of dizziness among patients presenting to the emergency department[J].Emerg Med J,2010,27(7):517-521.
[3] Kiyohara T,Kamouchi M,Kumai YA,et al.ABCD3 and ABCD3-I scores are superior to ABCD2 score in the prediction of short- and Long-Term risks of stroke after transient ischemic attack[J].Stroke,2014,45(2):418-425.
[4] Johnston SC,Rothwell PM,Nguyen-Huynh MN,et al.Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack[J].Lancet,2007,369(9558):283-292.
[5] 中华医学会神经科分会.各类脑血管病诊断要点[J].中华神经科杂志,1996,29(6):279.
[6] Casado V.Neurological patient care in emergency departments.A review of the current situation in Spain[J].Neurologia.,2011,26(4):233-238.
[7] Navi BB,Kamel H,Shah MP,et al.Application of the ABCD2 score to identify cerebrovascular causes of dizziness in the emergency department[J].Stroke,2012,43(6):1484-1489.
[8] Giles MF,Albers GW,Amarenco P,et al.Early stroke risk and ABCD2 score performance in tissue- vs time-defined TIA: a multicenter study[J].Neurology,2011,77(13):1222-1228.
[9] Sheehan OC,Merwick A,Kelly LA,et al.Diagnostic usefulness of the ABCD2 score to distinguish transient ischemic attack and minor ischemic stroke from noncerebrovascular events: the North Dublin TIA Study[J].Stroke,2009,40(11):3449-3454.

相似文献/References:

[1]黄立宏 李刚 冯小芳等. 15d-PGJ2对糖尿病大鼠脑缺血再灌注损伤小胶质细胞活化及神经细胞凋亡的影响[J].卒中与神经疾病杂志,2016,23(03):149.[doi:10.3969/j.issn.1007-0478.2016.03.001]
　Huang Lihong,Li Gang,Feng Xiaofang,et al. Effect of 15d-PGJ2 on the activation of microglias and the apotosis of neurons after the injury of acute cerebral ischemia reperfusion in diabetic rats[J].Stroke and Nervous Diseases,2016,23(03):149.[doi:10.3969/j.issn.1007-0478.2016.03.001]
[2]黄锦丰 凌国源 玉石等. L-选择素在缺血性脑卒中患者外周血中的表达及其意义[J].卒中与神经疾病杂志,2016,23(03):154.[doi:10.3969/j.issn.1007-0478.2016.03.002]
　Huang Jinfeng,Ling Guoyuan,Yu Shi,et al. L-selectin in peripheral blood of patients with ischemic cerebral stroke and its significance[J].Stroke and Nervous Diseases,2016,23(03):154.[doi:10.3969/j.issn.1007-0478.2016.03.002]
[3]袁波 谭李红 谭莉等. 介入栓塞与陀螺旋转式60钴放射治疗系统联合治疗颅内巨大动静脉畸形15例疗效观察[J].卒中与神经疾病杂志,2016,23(03):157.[doi:10.3969/j.issn.1007-0478.2016.03.003]
　Yuan Bo,Tan Lihong,Tan Li,et al. Clinical analysis of 15 cases combined treatment of endovascular embolization and gyro 60 cobalt radiation system in giant cerebral arteriovenous malformations[J].Stroke and Nervous Diseases,2016,23(03):157.[doi:10.3969/j.issn.1007-0478.2016.03.003]
[4]王慧玲 黄朝云. 脑卒中后抑郁合并认知损害的磁共振扩散张量成像研究[J].卒中与神经疾病杂志,2016,23(03):160.[doi:10.3969/j.issn.1007-0478.2016.03.004]
　Huiling,Huang Chaoyun.. A diffusion tensor imaging study in patients with post-stroke depression combined with cognitive impairmentWang[J].Stroke and Nervous Diseases,2016,23(03):160.[doi:10.3969/j.issn.1007-0478.2016.03.004]
[5]李岚. 肌电图定位定量电刺激治疗上肢周围神经损伤的临床分析[J].卒中与神经疾病杂志,2016,23(03):167.[doi:10.3969/j.issn.1007-0478.2016.03.006]
　Li Lan.. The clinical analysis of EMG quantitative electrical stimulation in the treatment of peripheral nerve injury of upper limb[J].Stroke and Nervous Diseases,2016,23(03):167.[doi:10.3969/j.issn.1007-0478.2016.03.006]
[6]李瑾 陈黛琪. 无创机械通气在重症肌无力危象治疗中的疗效[J].卒中与神经疾病杂志,2016,23(03):170.[doi:10.3969/j.issn.1007-0478.2016.03.007]
　Li Jin,Chen Daiqi.. Therapeutic effect of noninvasive mechanical ventilation in the treatment of myasthenia gravis crisis[J].Stroke and Nervous Diseases,2016,23(03):170.[doi:10.3969/j.issn.1007-0478.2016.03.007]
[7]强毅娜 高杰. 富亮氨酸胶质瘤失活1蛋白抗体阳性相关免疫脑炎1例临床分析并文献复习[J].卒中与神经疾病杂志,2016,23(03):174.[doi:10.3969/j.issn.1007-0478.2016.03.008]
　Qiang Yina,Gao Jie.. Clinical analysis of 1 patient with leucine-rich glioma inactivated-1 protein antibody positive limbic encephalitis:A case report and review of literature[J].Stroke and Nervous Diseases,2016,23(03):174.[doi:10.3969/j.issn.1007-0478.2016.03.008]
[8]宋楠 王红梅. 针吸型肌肉活检联合免疫荧光在假肥大型肌营养不良诊断中的应用[J].卒中与神经疾病杂志,2016,23(03):177.[doi:10.3969/j.issn.1007-0478.2016.03.009]
　Song Nan,Wang Hongmei.. The application of needle muscle biopsy combined with immunofluorescence in diagnosing of pseudohypertrophic muscular dystrophy[J].Stroke and Nervous Diseases,2016,23(03):177.[doi:10.3969/j.issn.1007-0478.2016.03.009]
[9]杨小华 李格 管萍. 脑出血迟发型血肿扩大的机制探讨和治疗对策[J].卒中与神经疾病杂志,2016,23(03):180.[doi:10.3969/j.issn.1007-0478.2016.03.010]
　[J].Stroke and Nervous Diseases,2016,23(03):180.[doi:10.3969/j.issn.1007-0478.2016.03.010]
[10]缪茂军 陈小武 曹学兵等. mTOR信号通路在左旋多巴诱发异动症中的作用及机制研究[J].卒中与神经疾病杂志,2016,23(03):182.[doi:10.3969/j.issn.1007-0478.2016.03.011]
　[J].Stroke and Nervous Diseases,2016,23(03):182.[doi:10.3969/j.issn.1007-0478.2016.03.011]

备注/Memo

备注/Memo:
 (2015-09-30收稿 2015-11-23修回)
更新日期/Last Update: 2016-06-24