参考文献/References:
[1] Lee RC,Feinbaum RL,Ambros V.The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14[J].Cell,1993,75(5):843-854.
[2] Bartel DP.MicroRNAs: genomics, biogenesis, mechanism, and function[J].Cell,2004,116(2):281-297.
[3] Moon JM,Xu L,Giffard RG.Inhibition of microRNA-181 reduces forebrain ischemia-induced neuronal loss[J].J Cereb Blood Flow Metab,2013,33(12):1976-1982.
[4] Chu B,Wu T,Miao L,et al.MiR-181a regulates lipid metabolism via IDH1[J].Sci Rep,2015,5:8801.
[5] 延佳佳,朱晓明.miR-181a 的研究进展[J].Chin J Clinicians,2013,12:5449-5451.
[6] Xu LJ,Ouyang YB,Xiong X,et al.Post-stroke treatment with miR-181 antagomir reduces injury and improves long-term behavioral recovery in mice after focal cerebral ischemia[J].Exp Neurol,2015,264:1-7.
[7] 王丽娟,凌英会,张晓东,等.microRNA调控动物发育的研究进展[J].家畜生态学报,2012,33(6):103-106.
[8] 曹小雨,杨秀芬.微RNAs与脑缺血/再灌注损伤的关系及对其机制影响的研究进展[J].医学综述,2016,22(16):3128-3133.
[9] 杨子岩,晏贤春,赵星成,等.微小RNAs与新生血管形成[J].心脏杂志,2015,27(1):102-105,109.
[10] 张婷婷,谢谦,邵家骧,等.
[10]MicroRNAs与脑卒中的研究进展[J].分子诊断与治疗杂志,2012,4(1):1-10.
[11] 韩滨,马晓峰,张超.急性脑卒中患者外周血单个核细胞来源的AChE相关的microRNAs的表达变化[J].天津医药,2016,44(10):1251-1254.
[12] Zeng L,Liu J,Wang Y,et al.MicroRNA-210 as a novel blood biomarker in acute cerebral ischemia[J].Front Biosci(Elite Ed),2011,3(4):1265-1272.
[13] Zeng L,Liu J,Wang Y,et al.Cocktail blood biomarkers: prediction of clinical outcomes in patients with acute ischemic stroke[J].Eur Neurol,2013,69(2):68-75.
[14] 曹琳,姚平波,张平,等.急性脑梗死患者外周血microRNA表达及其与炎症细胞因子的相关性[J].中国动脉硬化杂志,2015,23(3):277-280.
[15] Jia L,Hao F,Wang W,et al.Circulating miR-145 is associated with plasma high-sensitivity C-reactive protein in acute ischemic stroke patients[J].Cell Biochem Funct,2015,33(5):314-319.
[16] Li SH,Su SY,Liu JL.Differential regulation of microRNAs in patients with ischemic stroke[J].Curr Neurovasc Res,2015,12(3):214-221.
[17] Liu FJ,Kaur P,Karolina DS,et al.MiR-335 regulates Hif-1α to reduce cell death in both mouse cell line and rat ischemic models[J].PLoS One,2015,10(6):e0128432.
[18] Ouyang YB,Lu Y,Yue S,et al.miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo[J].Neurobiol Dis,2012,45(1):555-563.
[19] Selvamani A,Sathyan P,Miranda RC.An antagomir to MicroRNA let7f promotes neuroprotection in an ischemic stroke model[J].PLoS One,2012,7(2):e32662.
[20] Caballero-Garrido E,Pena-Philippides JC,Lordkipanidze T,et al.In vivo inhibition of miR-155 promotes recovery after experimental mouse stroke[J].J Neurosci,2015,35(36):12446-12464.
[21] Yang ZB,Li TB,Zhang Z,et al.The diagnostic value of circulating brain-specific MicroRNAs for ischemic stroke[J].Intern Med,2016,55(10):1279-1286.
[22] Sepramaniam S,Tan JR,Tan KS,et al.Circulating microRNAs as biomarkers of acute stroke[J].Int J Mol Sci,2014,15(1):1418-1432.
[23] Tan JR,Tan KS,Koo YX,et al.Blood microRNAs in low or no risk ischemic stroke patients[J].Int J Mol Sci,2013,14(1):2072-2084.
[24] Guo D,Liu J,Wang W,et al.Alteration in abundance and compartmentalization of inflammation-related miRNAs in plasma after intracerebral hemorrhage[J].Stroke,2013,44(6):1739-1742.
[25] Wang MD,Wang Y,Xia YP,et al.High serum MiR-130a levels are associated with severe perihematomal edema and predict adverse outcome in acute ICH[J].Mol Neurobiol,2016,53(2):1310-1321.
[26] Zhu Y,Wang JL,He ZY,et al.Association of altered serum micrornas with perihematomal edema after acute intracerebral hemorrhage[Z],2015:e0133783.
[27] Yuan B,Shen H,Lin L,et al.MicroRNA367 negatively regulates the inflammatory response of microglia by targeting IRAK4 in intracerebral hemorrhage[Z],2015:206.
[28] Kim JM,Lee ST,Chu K,et al.Inhibition of let7c microRNA is neuroprotective in a rat intracerebral hemorrhage model[Z],2014:0097946.
[29] Yang Z,Zhong L,Xian R,et al.MicroRNA-223 regulates inflammation and brain injury via feedback to NLRP3 inflammasome after intracerebral hemorrhage[J].Mol Immunol,2015,65(2):267-276.
[30] Muller AH,Povlsen GK,Bang-Berthelsen CH,et al.Regulation of microRNAs miR-30a and miR-143 in cerebral vasculature after experimental subarachnoid hemorrhage in rats[J].BMC Genomics,2015,16(1):1-8.
[31] Stylli SS,Adamides AA,Koldej RM,et al.miRNA expression profiling of cerebrospinal fluid in patients with aneurysmal subarachnoid hemorrhage[J].J Neurosurg,2017,126(4):1131-1139.
[32] Xu HF,Fang XY,Zhu SH,et al.Glucocorticoid treatment inhibits intracerebral hemorrhage?induced inflammation by targeting the microRNA 155/SOCS 1 signaling pathway[J].Mol Med Rep,2016,14(4):3798-3804.
[33] Zhao S,Gong Z,Zhang J,et al.J stroke cerebrovasc Dis[J].doi:10.1016/j.jstrokecerebrovasdis,2015,24(8):1709-1714.
[34] Dai D,Lu Q,Huang Q,et al.Serum miRNA signature in Moyamoya disease[J].PLoS One,2014,9(8):e102382.