[1]黄锦丰 凌国源 玉石等. L-选择素在缺血性脑卒中患者外周血中的表达及其意义[J].卒中与神经疾病杂志,2016,23(03):154-156.[doi:10.3969/j.issn.1007-0478.2016.03.002]
　Huang Jinfeng,Ling Guoyuan,Yu Shi,et al. L-selectin in peripheral blood of patients with ischemic cerebral stroke and its significance[J].Stroke and Nervous Diseases,2016,23(03):154-156.[doi:10.3969/j.issn.1007-0478.2016.03.002]
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《卒中与神经疾病》杂志[ISSN:1007-0478/CN:42-1402/R]

卷:
第23卷
期数:
2016年03期
页码:
154-156
栏目:
论 著
出版日期:
2016-06-24

文章信息/Info

Title:
 L-selectin in peripheral blood of patients with ischemic cerebral stroke and its significance
作者:
 黄锦丰 凌国源 玉石等
 530021 南宁,中国人民解放军第三0三医院神经外科[黄锦丰 凌国源 玉石 陈文斗(通信作者)]
Author(s):
 Huang Jinfeng; Ling Guoyuan; Yu Shi; et al.
 Department of Neurosurgery, the 303rd Hospital of PLA, Nanning 530021
关键词:
 ; L-选择素 缺血性脑卒中 炎症
Keywords:
 ; L-selectin Ischemic cerebral stroke Inflammation
分类号:
R743
DOI:
10.3969/j.issn.1007-0478.2016.03.002
文献标志码:
A
摘要:
 目的 探讨L-选择素在缺血性脑卒中患者中的表达及其意义。方法 选择缺血性脑卒中患者(病例组)和正常健康体检者(对照组)各50例,以甘油醛-3-磷酸脱氢酶(GAPDH)为内参,运用半定量RT-PCR技术检测研究对象外周血中L-选择素的表达水平。结果 与对照组比较,病例组L-选择素水平明显升高(2.96±0.71 vs 1.22±0.46,P<0.01)。结论 L-选择素在缺血性脑卒中患者外周血中表达增加,提示L-选择素可能与缺血性脑卒中的发病有关。
Abstract:
 ObjectiveTo explore the expression of L-selectin in peripheral blood of patients with ischemic cerebral stroke, and the relationship between L-selectin and the ischemic stroke.Methods The expression of L-selectin in peripheral blood of 50 patients with ischemic cerebral stroke, as case group, and 50 normal subjects, as control group, was detected using the semi-quantitative RT-PCR technology, and the expression of glyceraldehyde 3 phosphate dehydrogenase(GAPDH)was used as the internal control.Results The expression of L-selectin in patients with ischemic cerebral stroke was significantly higher than that in normal subjects(2.96±0.71 vs 1.22±0.46, P<0.01).Conclusion The expression of L- selectin was higher in patients with ischemic cerebral stroke. It is inferred that L- selectin was probably involved in the onset of ischemic cerebral stroke.

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备注/Memo

备注/Memo:
 (2016-02-19收稿 2016-05-04修回)
更新日期/Last Update: 2016-06-24